Grapefruit and prescription drugs
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Grapefruit and prescription drugs
Nov 26, 2012
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Grapefruit interacts with: Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin).Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).Some organ-transplant rejection drugs, such as Neoral and Sandimmune capsule or oral solution (both cyclosporine).Some anti-anxiety drugs, such as BuSpar (buspirone).Some corticosteroids that treat Crohn’s disease or ulcerative colitis, such as Entocort EC and Uceris tablet (both bude
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Grapefruit interacts with: Some statin drugs to lower cholesterol, …
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FacebookAngela Pharmd
Grapefruit contains compounds (furanocoumarins) that block an enzyme in the gut and liver called CYP3A4. This important enzyme helps break down many medications, including some forms of oestrogen and progesterone. When CYP3A4 is stopped from working the following happens: 👉 More of the drug remains in your system 👉 The effect becomes less predictable 👉 You may absorb more than intended, including in HRT case spikes in hormone levels This is the same mechanism behind grapefruit warnings for st
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