Patients in Wales face a high risk of increased harm if the NHS does not urgently improve performance and productivity in core services, independent experts have warned. The Ministerial Advisory Group ...

Riley and colleagues discuss the importance of presenting the uncertainty around risk estimates provided by clinical prediction models.1 They describe how uncertainty and bias can be caused by poor ...

Women living in US states that have abortion bans, such as Louisiana or Texas, are almost at twice the risk of dying during pregnancy, childbirth, or shortly after giving birth than women in states ...

A review of gender dysphoria commissioned by Donald Trump has concluded that the evidence “remains very low across all intervention types” but made no mention of the research needed to meet the needs ...

Vanderslott discusses several shortcomings of covid-19 vaccination that need to be tackled in preparation for future pandemics.1 My colleagues and I have identified an additional area of concern.2 We ...

Robert F Kennedy Jr, now the US health secretary, ordered medical journals to “start publishing real science and stop retracting the real science.” Now, after delivering 100 days of global disruption, ...

A drug that was approved last year for uterine fibroids is now available for patients of reproductive age who have previously had medical or surgical treatment for endometriosis. In final draft ...

Ruth Segovia y Mayoral describes her experience of living with immune thrombocytopenia and why she wishes health professionals were able to prescribe rest I have always resisted defining myself by my ...

Pope I, Clark LV, Clark A, et al. Cessation of Smoking Trial in the Emergency Department (COSTED): a multicentre randomised controlled trial. Emergency Medicine Journal 2024;41:276-282. To read the ...

Launer’s role playing exercise—in which he shared the thoughts going through his mind during a difficult consultation—raises issues relevant to the care experienced by many people with rare conditions ...

What you need to know Adrenal insufficiency is the inadequate production of the hormone cortisol from the adrenal glands. Global prevalence ranges from 0.4/100 000 (South Korea) to 15-22/100 000 ...

The UK is not prepared to cope with the likely effects of a warming climate, such as escalating deaths and health system disruption, independent advisers have warned the government. In its 2025 report ...