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When it comes to tau tangles, cortical deposits receive the lion’s share of scientists’ attention, but it is the tiny subcortical regions where tangles originate that might set the course for ...

This variant is one of 31 intronic variants in SORL1 that compose a haplotype associated with a reduced risk of Alzheimer’s disease and with certain AD-related endophenotypes in people of East Asian ...

Although efforts to identify biomarkers for Alzheimer's disease are advancing rapidly, many still struggle to obtain information from populations other than non-Hispanic white people. At the Human ...

In the Alzheimer’s field, conventional wisdom holds that the growth of amyloid plaques in the brain soaks up Aβ42 peptide, depleting it from cerebrospinal fluid. Now, in the February 12 Nature Aging ...