New 25% trade tariffs on goods from Canada and Mexico went into effect early Tuesday after President Donald Trump declined to extend a 30-day pause in a move the president says aims to quell the flow of illegal drugs like fentanyl into the U.S. The new assessments also include a 10% tariff on Canadian energy products.

New U.S. tariffs on imports from Mexico, Canada, and China take effect Tuesday, marking the most aggressive use of trade sanctions in decades.

Beijing retaliated with tariffs on many U.S. farm exports, and Justin Trudeau said Canada would slap tariffs on $100 billion of American goods over the next 21 days.