Injured players, inactives, latest injury updates
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Even with the 49ers’ offense firing on all cylinders and nearly every weapon available, he’s stepping up and proving himself as a serious contributor. That’s why he’s having the best season of his career, recording a career-high total of eight touchdowns.
Siran Neal is hardly a household name, but the special teams gunner has been one of the most important players for SF this season.
Niners Wire on MSN
49ers players fall in final 2026 Pro Bowl Games fan voting update
The fan voting for the 2026 Pro Bowl Games has come to a close. Here's where a few San Francisco 49ers players landed in the final tally.
FB Kyle Juszczyk, TE George Kittle, RB Christian McCaffrey, T Trent Williams, LB Luke Gifford, and LS Jon Weeks were selected for the 2026 Pro Bowl Games in San Francisco, California.
The only active 49ers defenders to ever start a playoff game in their careers are safety Ji’Ayir Brown and cornerback Deommodore Lenoir.
The San Francisco 49ers have released the list of inactive players for their Week 16 matchup against the Indianapolis Colts. These seven players will not
Chicago Bears head coach Ben Johnson is opening up about Caleb Williams ahead of the team's San Francisco 49ers game.
The 49ers dealt a devastating blow to the Colts' playoff hopes on Monday night and there was plenty of blame to go around in Indianapolis.
Colts Wire on MSN
4 Colts players out v. 49ers; one key offensive player questionable
The Indianapolis Colts released their final injury report ahead of a crucial Monday Night game against the San Francisco 49ers. Four players have been ruled out, while two are questionable. Among those who are questionable are DeForest Buckner (neck) and Bernhard Raimann (elbow).
San Francisco 49ers quarterback Brock Purdy was named the NFC Offensive Player of the Week for his five-touchdown game against the Indianapolis Colts.