While the Bemis-Murcko approach to scaffold analysis has remained the go-to definition for computational medicinal chemistry for the past few decades, it is not without its shortcomings. New research ...

While the Bemis-Murcko approach to scaffold analysis has remained the go-to definition for computational medicinal chemistry for the past few decades, it is not without its shortcomings. New research ...

Scaffold proteins have an important role in regulating immune-cell signalling. This Review provides an overview of the numerous functions that have been attributed to scaffold proteins, and discusses ...

(Link) This work reviews the literature on analogy, introduces a new model of analogy, and presents a series of experiments that test and confirm the utility of this model to describe and predict ...

A New Haven medtech startup is headed to market with its first device, a soft tissue scaffold that can be completely broken down by the body and aims to speed the recovery time for common orthopedic ...