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Predictions, picks and odds for NFL Week 18 game

NFL Week 18 picks: Our experts face off on Panthers at Buccaneers, Seahawks vs. 49ers and more

The final week of the 2025 NFL regular season is here, and there is plenty to be figured out.

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· 14h · on MSN

NFL straight-up picks Week 18: Nothing matters except these 5 games

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NFL Week 18 Predictions & Picks – Underdog Best Bets Against the Spread

NFC West will be decided by 49ers' offense taking on Seahawks' smothering defense

Nate Tice & Charles McDonald break down the upcoming Week 18 matchup between the San Francisco 49ers and Seattle Seahawks.

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49ers vs. Seahawks Injury Report – Week 18, 2025

49ers bold predictions for huge Week 18 clash with Seahawks

Seahawks vs. 49ers prediction, odds, pick for Week 18 NFC West decider

The Seattle Seahawks most recently took down the Carolina Panthers 27-10 in Week 17 for their sixth-consecutive victory.

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Seahawks bold predictions for NFC West decider against 49ers

Seahawks make a bunch of roster moves ahead of Week 18

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NFL Week 18 picks against the spread: Why I’m trusting King Henry and the Ravens

Picking the Ravens over the Steelers is almost too easy. We also like the Seahawks over the 49ers and Bucs over Panthers in critical games.

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Is there a Thursday Night Football game tonight? NFL Week 18 schedule

There has been an NFL game every Thursday night since Week 1. But is there a "Thursday Night Football" game tonight?