A new CRISPR-based one-off procedure that lowers "bad" cholesterol has been approved to enter Phase I human trial. If ...

Schizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia.

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of ...

Data from a major U.S. clinical trial from the Alliance for Clinical Trials in Oncology has uncovered a genetic factor that may inform how to optimize the dosing of abiraterone, a widely used hormone ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci with human genomic DNA. The method integrates fragments over 200 kbp.

Data from a major U.S. clinical trial from the Alliance for Clinical Trials in Oncology has uncovered a genetic factor that may inform how to optimize the dosing of abiraterone, a widely used hormone ...