Israel faced retaliation from Iran after launching missiles against Tehran's leadership and energy infrastructure as part of "Operation Rising Lion" this weekend. Iran's military responded with a wave of missile strikes against Israel,

At least ten people were killed in Israel overnight, after multiple Iranian missiles evaded the country's advanced defense systems. Explosions rocked Tehran, but casualties weren't immediately clear.

Emergency services say ten have been killed in Israel, while Iranian state media have given little information about casualties in Iran.

The U.S. says it wasn't involved in the strikes on Iran, but three American officials told NBC News the U.S. is assisting in shooting down Iranian missiles and projectiles targeting Israel.

Israel’s ongoing attacks on Iranian nuclear sites killed 78 people and wounded more that 320 on Friday, said Iran’s ambassador to the United Nations. The strikes killed generals and scientists, but the ambassador told the U.N. Security Council that “the overwhelming majority” of victims were civilians.

At least 13 Israelis have now died in the hostilities between the Jewish state and Iran that began last week. Iranian strikes carried out overnight against Israel took at least 10 lives, according to Israel’s Magen David Adom rescue service.

The retaliatory strikes came on Saturday, a day after Israel killed top Iranian military leaders and scientists and destroyed an aboveground nuclear enrichment plant near Natanz.

US intelligence has reported that Iran has 2,000 ballistic missiles, many of which are capable of carrying 900 kg warheads. Iran's goal is for the number of its missiles to exceed the number of Israeli air defense interceptors.