Observational data in inflammatory bowel disease (IBD) supported the safety of JAK inhibitors versus TNF inhibitors in terms of serious outcomes -- including blood clots, major heart events, and ...

In patients with deficient mismatch repair/microsatellite instability-high (dMMR/MSI-H) metastatic colorectal cancer (CRC) who received immune checkpoint inhibitors, changes in circulating tumor DNA ...

ALAMEDA, Calif.--(BUSINESS WIRE)--Exelixis, Inc. (Nasdaq: EXEL) today announced positive topline results from the STELLAR-303 phase 3 pivotal trial in which zanzalintinib in combination with ...

Durability follow-up data of the single-arm cohort in first-line KRAS G12C-mutant non-small cell lung cancer (NSCLC) patients, regardless of PD-L1 expression, who received ifebemtinib + garsorasib ...

The use of an investigational topical BRAF-inhibiting gel appeared to be effective in treating acneiform rash in patients with advanced colorectal cancer who were treated with an epidermal growth ...

The car frame is the main supporting framework to which all other parts of the car are connected. Because a car frame is made of metal, it can rust over time. The good news is that it can be repaired, ...

BRAF V600E-mutant metastatic CRC is associated with poor clinical outcomes, with a median overall survival of 17 months. Factors influencing overall survival include metastasectomy and ECOG ...

The combination treatment specifically targets KRAS-mutated metastatic colorectal cancer (CRC) to improve progression-free survival. The approval was based on results from CodeBreaK 300, a phase 3, ...

(RTTNews) - MAIA Biotechnology, Inc. (MAIA), a clinical-stage biopharmaceutical company, on Tuesday announced a clinical supply agreement with BeiGene to evaluate the efficacy of its lead drug ...

Experienced boiler operators know that oxygen can cause localized, severe corrosion in steam boiler systems through a process called oxygen pitting. This occurs when dissolved oxygen in the water ...

BOSTON--(BUSINESS WIRE)--DeepCure, a therapeutics company using AI to discover novel therapies for inflammation and immune diseases, announced today the discovery of potent, selective oral small ...

ICI-based combinations, especially with TKI, improved survival in heavily pretreated MSS mCRC patients, showing a median OS of 11.8 months and PFS of 4.6 months. Liver metastasis negatively impacted ...