Medical Xpress

Portable tuberculosis test achieves 100% sensitivity and specificity in clinical samples

Princeton University and collaborators have developed SHINE-TB, a one-sample, parallelized reaction amplification and detection CRISPR assay that detects Mycobacterium tuberculosis directly from ...
ascopubs.org

Improving the Sensitivity-Specificity Balance of Human Papillomavirus Testing on Self- and Clinician-Collected Samples in South Africa

Women living with and without HIV, age 30-65 years, were recruited in South Africa. Self-collected vaginal samples and clinician-collected cervical samples were tested with Xpert HPV, an assay that ...
Nature

SUMO monoclonal antibodies vary in sensitivity, specificity, and ability to detect types of SUMO conjugate

Monoclonal antibodies (MAb) to members of the Small Ubiquitin-like modifier (SUMO) family are essential tools in the study of cellular SUMOylation. However, many anti-SUMO MAbs are poorly validated, ...
ascopubs.org

Sensitivity and specificity of 61 commercial disease detection products: A systematic review and meta-analysis of 80 cohorts with approximately 445,000 enrolled samples.

Effects of common nutraceutical supplements marketed for cancer prevention on tumor cell growth.
Nature

Evaluation of sensitivity and specificity of Kato-Katz and circulating cathodic antigen in terms of Schistosoma japonicum using latent class analysis

This study was approved by the institutional review boards of Rhode Island Hospital (Providence, RI, USA) and the Research Institute of Tropical Medicine, Manilla, The Philippines. All participants ...