Brock Purdy is closing in on a return from injury for the 49ers, with an expected return by NFL Week 11. What about Mac Jones? Find out.

The San Francisco 49ers released their latest injury updates headed into the Week 10 contest versus the Los Angeles Rams.

The Los Angeles Rams picked up a win over the San Francisco 49ers on Sunday, but a key player is now dealing with an injury.

Defensive end Bryce Huff was back in a limited fashion after working through a hamstring injury he suffered in the 49ers' Week 7 win over the Atlanta Falcons. He missed Weeks 8 and 9, but his return to practice is a good sign that he's trending toward playing in Week 10.

San Francisco 49ers head coach Kyle Shanahan provided final injury updates on QB Brock Purdy, WR Ricky Pearsall and others, and discussed the team's game plan heading into their matchup against the Los Angeles Rams.

San Francisco 49ers rookie Mykel Williams reportedly confirmed to have suffered a torn ACL, which will end his season.

ESPN's Jeremy Fowler was the first to report that San Francisco 49ers head coach Kyle Shanahan's fears from Sunday afternoon were confirmed—rookie defensive end Mykel Williams suffered a torn ACL and will undergo season-ending surgery.

After the San Francisco 49ers’ Week 9 win over the New York Giants, head coach Kyle Shanahan said, “We’re worried it’s an ACL” when referring to first-round pick Mykel Williams’ injury.