The San Francisco 49ers couldn’t have been much worse in a Week 10 loss to the Los Angeles Rams. Here are the highlights.

The Los Angeles Rams (6-2) will be hosted by the San Francisco 49ers (6-3) in Week 10 of the NFL season, and here’s our how to watch guide! This game should have big implications for the NFC West and the NFC as a whole as both the Rams and 49ers have looked like top-end teams throughout their first set of games of the season.

Even though the odds of the San Francisco 49ers completing the comeback still would have been slim, Fox's officiating analyst said the referee crew's mistake late in Sunday's loss to the Rams took away a key first down.

The 49ers cannot afford for Purdy to be hurt long-term, which is probably why Shanahan has chosen instead to be cautious with the signal caller. The star quarterback might just need a couple more weeks to fully heal, which shouldn't be an issue for the team.

The Los Angeles Rams were in Santa Clara today for their second meeting with the San Francisco 49ers, a rematch of their Week 5 showdown. The Rams were seeking their fourth straight victory since that loss to the 49ers, playing like one of the best teams in the league.

Matthew Stafford and the Rams pull away in the fourth quarter to defeat the rival San Francisco 49ers 42-26 for their fourth consecutive victory.

A banner blasting the prospect of immigration enforcement at the Super Bowl flew in Santa Clara on Sunday amid tensions over the musician's upcoming performance.

The Los Angeles lead the San Francisco 49ers by a score of 21-7 after the first half of play. L.A. dominated the first quarter and the majority of the first half as they were leading 21-0 with still 13:41 to go before halftime.

The San Francisco 49ers announced several roster moves on Saturday, as the team prepares for its Week 10 matchup against the Los Angeles Rams. Offensive lineman Ben Bartch has been activated from the injured reserve list.