After the 49ers upset the Rams earlier in the season, Sean McVay claimed victory this time around in his coaching rivalry with his friend, Kyle Shanahan, thanks to Matthew Stafford.  The Rams' quarterback had a stellar performance on Sunday,

Seattle earned their ninth-straight win over the Cardinals, their fourth-straight win overall, and their second-straight blowout victory. Seahawks are 7-2 and will face off against the similarly 7-2 Rams next week for first place in the NFC West.

The Los Angeles Rams are in Santa Clara today for their second meeting with the San Francisco 49ers, a rematch of their Week 5 showdown. The Rams are seeking their fourth straight victory since that loss to the 49ers, playing like one of the best teams in the league.

Matthew Stafford passes for 280 yards and four touchdowns as the Rams defeat the 49ers 42-26 to set up an NFC West showdown with the Seattle Seahawks next week.

The Seattle Seahawks improved to 7-2 on the year with their ninth-straight win over the Arizona Cardinals, their fourth-straight win this season, and their second-straight blowout with a 44-22 victory. Seattle kept the momentum going in a massive way by delivering yet another curb-stomping to an NFL opponent.

Highlights from the Week 10 matchup between the Los Angeles Rams and the San Francisco 49ers during the 2025 NFL season.

There are three NFL games in Week 10's afternoon slot, which means we can take one wager from each game and create a three-leg NFL parlay at BetMGM. The highlight of Week 10's afternoon games is the Los Angeles Rams at San Francisco 49ers rivalry showdown,

Find out how to watch the NFL Week 10 game between the Seattle Seahawks and Arizona Cardinals, as well as the latest odds and updated injury report.

Highlights from the Week 10 matchup between the Arizona Cardinals and the Seattle Seahawks during the 2025 NFL season.

Rams star wide receiver Davante Adams exited the Rams' NFC West showdown against the 49ers in the fourth quarter due to an oblique injury. He was ruled questionable to return, though Sean McVay said the Rams being up multiple scores may have impacted the decision to not have him return.