The Seattle Seahawks, Los Angeles Rams, and San Francisco 49ers all have big aspirations for this season, but only one of them can win the division. The Arizona Cardinals, however, have fallen short in the division so far despite aiming to return to the playoffs.

The biggest questions facing the Tampa Bay Buccaneers coming out of the bye week surrounded the offense.Could Baker Mayfield get back on track after inconsistent games against the Detroit Lions and New Orleans Saints?

The 49ers have been decimated on the defensive side of the football, including key players in linebacker Fred Warner, edge rusher Nick Bosa and rookie first-round-rookie defensive lineman Mykel Williams all out for the season due to injuries. And the depleted defense struggled to contain L.A.’s running game.

The Bucs are 6–2 and feeling good, but there’s a harsh reality tucked behind that shiny record: The next three weeks could define their season. They’ll host the Patriots, then head to Buffalo and Los Angeles to face the Rams.

The Tampa Bay Buccaneers are coming off their allotted bye week and will enter a tough stretch featuring the New England Patriots, Buffalo Bills and Los Angeles Rams. The Bucs have been injury-tested in 2025 but remain in the driver's seat in the NFC South hunt ahead of the 5-4 Carolina Panthers.

Five key talking points for Week 10 of the 2025 NFL season including the Colts facing the Falcons in Berlin and the Packers hosting the Eagles on Monday Night Football.

Fox Sports NFL analyst Tom Brady had a wild reaction to Matthew Stafford's no-look touchdown pass in the Rams-49ers game.

The San Francisco 49ers finished their Week 10 contest with a 42-26 loss against the Los Angeles Rams at Levi's® Stadium.

So, yes, the Bucs are vulnerable. And, more ominously, they’ve got road games against the Bills (6-2) and Rams (6-2) the next two weeks. A three-game losing streak for a banged-up roster is not out of the question. That means the New England game looms large.