Alternative polyadenylation is a vital gene function regulatory mechanism, occurring in more than 60% of human genes. The process is required for the synthesis of diverse mRNAs and proteins from a ...

The regulated translation of messenger RNAs is crucial for many developmental processes, including oocyte maturation, establishment of the embryonic axes, and regulation of 'synaptic memory' in the ...

Adult stem cells are essential for tissue homeostasis. In skeletal muscle, muscle stem cells (MuSCs) reside in a quiescent state, but little is known about the mechanisms that control homeostatic ...

Recent research on Arabidopsis thaliana flowering may sow the seed of new connections between plant and human reproduction. Gordon Simpson and Caroline Dean at the John Innes Center in Norwich, UK, ...

A team led by Dr. Eddie Imada, assistant professor of research in pathology and laboratory medicine, has been awarded a three-year, $1.5 million United States Department of Defense grant for research ...

RNA-binding proteins (RBPs) are central regulators of post-transcriptional gene expression. They modulate key aspects of mRNA metabolism—such as splicing, ...