A causative role for Notch signalling is well established in T cell acute lymphoblastic leukaemias (T-ALLs), which have activating mutations in the Notch genes resulting in a constitutively active ...

The role of the Notch pathway during animal neural development is best understood in fruit flies, where Notch has been shown to inhibit differentiation by lateral signaling and regulate cell fate ...

Notch signalling is involved in the cell-cell communication process via influencing the patterns of gene expression and differentiation. Notch pathway maintains stem cell populations and regulates ...

The notch signaling pathway plays a major role in regulating various cellular processes during development, therefore dysregulation of this pathway can lead to disease. This basic signaling pathway ...

Notch and the other founders of Mojang are selling their studio and Minecraft to Microsoft for $2.5 billion. In a blog post announcing the sale, Mojang's Owen Hill broke down the reasons for the sale, ...

Minecraft--one of the biggest games in the world and a touchstone of untold millions of childhoods--turns 10 this year. It's a little hard to believe, especially since it seems so recently that the ...