Nerve sheath tumors grow on the protective covering around nerves. They can affect cranial, spinal, or peripheral nerves and usually are benign. Symptoms can include pain, numbness or tingling, ...

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that arise from benign plexiform neurofibroma (PN) and borderline atypical neurofibroma (AN) in the setting of ...

Mitotic checkpoint maintains genomic integrity before mitosis. Numerous observations have suggested that mitotic abnormalities produce chromosomal instability and aneuploidy. In MPNST, complex ...

Combining a pair of experimental drugs may help treat malignant peripheral nerve sheath tumors with fewer harmful side effects, according to preliminary animal studies. Combining a pair of ...

Last summer Len Barchanowicz, 45, experienced sharp pangs in his neck that felt like a pinched nerve. After about a week, his symptoms intensified and he experienced chest pain and trouble breathing ...

Two recent studies describe the potential of liquid biopsies to identify and track tumor growth in two very different cancers: bladder cancer and peripheral nerve tumors. Despite the differences ...

A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and Institut Català d'Oncologia (ICO) has studied alterations in the KRAS gene in colorectal cancer by combining genomic ...

A new case report was published in Volume 12 of Oncoscience on December 23, 2025, titled “Solitary diffuse-type giant neurofibroma arising from the sciatic nerve in a 13-year-old: A rare occurrence.” ...

Eftilagimod Alpha Plus Pembrolizumab in First-Line Metastatic Non–Small Cell Lung Cancer: Results From a PD-L1–Unselected Population in the TACTI-002 Study This investigator-initiated, phase II, ...

The human polyomavirus, JC virus, has recently been associated with several human CNS tumors, including medulloblastomas and a broad range of glial-origin tumors. This ubiquitous virus is the ...

Liquid biopsies detect tumor DNA in blood or urine samples. Two studies led by Washington University School of Medicine in St. Louis describe the potential of liquid biopsies to identify and track ...