Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

SportsLine's proven computer model has identified it's top NFL picks for Week 17 divisional rivalry matchups at DraftKings

With the NFL's regular season just a handful of days away from wrapping up, a lot is riding on number of Week 18 matchups. 12 teams have already locked up playoff spots heading into this weekend's finales.

Watch the NFL Week 18 Buffalo Bills vs. New York Jets game in person with ticket info, game time, stats and how to view information.

Following their 20-13 win over the Kansas City Chiefs in Week 17, the Denver Broncos are now considered home favorites going into a regular season finale against the Los Angeles Chargers in Week 18.

The Cardinals are 3-13 and have lost eight games in a row, including a 45-17 home loss to the Rams in Week 14. The Rams are 11-5 and coming off a loss on Monday night. The Cardinals and Rams kick off Sunday afternoon from SoFi Stadium in Inglewood,

We've reached the final week of the regular season. Here's an early look at some predictions and picks for the 2026 NFL playoffs.