During migration in tissue in vivo or in culture in a three-dimensional (3D) extracellular matrix (ECM), endothelial cells, fibroblasts and tumour cells exhibit a characteristic complex shape that ...

The novel cardiac myosin inhibitor aficamten improved peak oxygen uptake in symptomatic obstructive hypertrophic cardiomyopathy (HCM), the pivotal SEQUOIA-HCM trial showed. At 24 weeks, the mean ...

"This process appears to be regulated by myosin-binding protein-C (cMyBP-C), which is a heart muscle protein," study author Kerry McDonald said. "Our study investigated its role in cardiac muscle ...

Each year, about 14,000 people in the United States are diagnosed with glioblastoma, one of the deadliest primary brain tumors. With standard treatments of surgery, radiation, and chemotherapy ...

Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy ...

Secondary efficacy analyses of the pivotal SEQUOIA-HCM trial continued to favor aficamten, supporting a potential role for another cardiac myosin inhibitor in obstructive hypertrophic cardiomyopathy ...

Scientists have developed an extremely accurate imaging technique for looking inside the machinery of a cell and have found that molecules of myosin "walk" in a fashion very much like a human.

JUPITER, Fla., July 7, 2025 /PRNewswire/ -- Myosin Therapeutics, a clinical-stage biotechnology company advancing first-in-class therapies targeting molecular motor proteins, announced the publication ...

Bristol-Myers Squibb Company (NYSE:BMY) is one of the cheap S&P 500 stocks to invest in now. On January 12, Bristol-Myers ...

In a recent study published in Nature Communication, researchers employed artificial intelligence (AI)-driven virtual screening to discover 'F10', a novel cardiac-specific myosin inhibitor for ...