Cellular life hinges on a network of hollow cables called microtubules dynamically lengthening and shortening according to the needs of the moment. During cell division, for instance, these cables ...

Microtubule nucleation is a fundamental process in eukaryotic cells, underpinning the formation of the cytoskeletal network that is critical for cell division, intracellular transport and overall ...

Inside every cell, a network of tiny filaments, called the microtubule cytoskeleton, helps maintain the cell's shape, allows it to divide, and transports vital materials from one part of the cell to ...

Scientists found out how naturally unstable filaments decide whether to grow or to shorten. In a groundbreaking study published today in the journal Proceedings of the National Academy of Sciences ...

As γ-TuRC starts the nucleation process and as the microtubule begins to form, it cleverly changes its shape. Initially in an open state, it progressively closes as the microtubule grows. The change ...

Prefoldin 5 stabilises neuronal microtubules and suppresses Tau-mediated neurotoxicity, offering a potential therapeutic target for tauopathies.