Tom Brady awards Los Angeles Rams QB Matthew Stafford with the LFG Player of the Game after his four touchdown performance against the San Francisco 49ers.

The NFC West is loaded at the top, and two of the division's contenders meet on Sunday when the 6-3 San Francisco 49ers host the 6-2 Los Angeles Rams. This is the second meeting between these two rivals, as the 49ers won the Week 5 matchup 26-23 in overtime on Thursday Night Football.

The Los Angeles Rams collected a 42-26 win on the road against NFC West rivals San Francisco 49ers on Sunday, but not before a worrisome injury development. In the fourth quarter of the contest, Los Angeles star wide receiver Davante Adams was seen leaving the field with an apparent upper-body injury.

WOODLAND HILLS, Ca. The Los Angeles Rams have finalized their roster before their week ten matchup against the San Francisco 49ers. Most of these moves were expected after the team committed to having a new approach in their kicking unit. McVay wanted Jake McQuaide as his long snapper due to his previous work and familiarity.

Expert recap and game analysis of the Los Angeles Rams vs. San Francisco 49ers NFL game from November 9, 2025 on ESPN.

San Francisco tight end George Kittle explained why the 49ers' games against the Los Angeles Rams stand out to him ahead of their Week 10 matchup.

Los Angeles Rams' Matthew Stafford found Davis Allen for a touchdown against San Francisco 49ers, reached 400 career passing touchdowns.

Coming back to win after being down 21-0 early was too much for the 49ers to overcome against the Rams. Here are the seven takeaways that stood out the most in their loss.