Brenig has launched an early Phase 1 trial to evaluate BT-409, its experimental small molecule therapy, in healthy volunteers ...
The inflammasome, a multiprotein complex, plays a crucial role in the field of innate immunity. It is activated by ...
A Signaling Nexus for Both Good and Ill, It’s Pathways of Pathogenic and Therapeutic Importance Are Still Being Identified A recent paradigm shift in medicine started with the finding that several ...
Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is ...
In a recent study published in the Molecular Psychiatry journal, researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing ...
NEWTON, Mass.--(BUSINESS WIRE)--Inflammasome Therapeutics (https://www.inflam.com/), a clinical-stage biotech company developing novel, first-in-class dual ...
(Nanowerk News) Excessive activation of inflammasomes is associated with various diseases, including gout, Alzheimer's disease, atherosclerosis, and type 2 diabetes. Given the pivotal role of ...
Inflammasomes are huge, multi-protein complexes inside cells that spark inflammation when they sense danger. Inflammasomes can also sound the alarm when no pathogens are present, contributing to ...
This study was collaboratively performed by Dr. Shu-Hong Yu, Dr. Long-Ping Wen, and Dr. Kun Qu from the University of Science and Technology of China, with Professor Yang Lu from the Hefei University ...
Neuronal inflammation is the common denominator in diseases such as Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, Age-Related Macular Degeneration and Type 2 Diabetes, that have ...
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