Heat Shock Factor 1 (HSF1) is a pivotal transcription factor that orchestrates the cellular response to proteotoxic and various other forms of stress. By regulating a comprehensive transcriptional ...
Researchers have identified a novel Heat Shock Factor (HSF), designated as HSF5, which plays a crucial role in the completion of meiosis and the activation of genes essential for sperm formation. This ...
Deletion of hsf5 in mice results in the impaired development of testis (left), and the absence of spermatids and spermatozoa (right), which leads to the failure of sperm formation. Kumamoto University ...
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