The phrase any given Sunday exists for a reason, but from the Green Bay Packers‘ perspective, losing to the Panthers as 13.5-point home favorites is inexcusable.

There are 12 games on the NFL schedule today with the Atlanta Falcons and Indianapolis Colts starting things off in Germany. The Las Vegas Raiders and Denver Broncos began Week 10 on Thursday night. Here are the games today:

Preview the Week 10 matchup between the Green Bay Packers and Philadelphia Eagles with predictions, odds, over/under, spread, betting lines and more.

Officially, based on the pregame spread, it is the largest upset loss in the NFL in roughly two years. For the Packers themselves, it is tied for the worst Green Bay defeat since the NFL actually became a thing in the public consciousness. The Packers, as an organization, simply do not usually lose games like this. It's not who they are.

The Packers have an "immature" performance in loss to the Panthers and "need to grow up," ESPN's Dan Orlovsky said on "The Pat McAfee Show."

The busy visit schedule for free agent cornerback Asante Samuel Jr. will include a stop in Green Bay this week. According to Jeremy Fowler of ESPN, Samuel is scheduled to visit the Carolina Panthers on Wednesday,

A major Green Bay Packers injury could lead to the team making a trade deadline deal with the Cleveland Browns or Tennessee Titans.

The Las Vegas Raiders traded the veteran wide receiver to the Jacksonville Jaguars for fourth and sixth round draft picks in 2026, first reported by national outlets. The Jaguars confirmed the move later in the morning Nov. 4.