Genotype–phenotype databases contain data on genetic variants and associated phenotypes. In medical contexts, such databases are focused on disease-causing mutations and resulting diseases or ...

Discover the latest articles and news in related subjects. For the majority of common human diseases, only a small fraction of the heritability can be attributed to known genetic variation. A widely ...

Please provide your email address to receive an email when new articles are posted on . Fast track designation has been granted to an antigen-specific immunotherapy for young people with type 1 ...

The characteristics of an organism emerge through complex interactions of its genetic make-up and the effects of the environment. This article discusses this terminological distinction in genetics - ...

New research shows that while a three-base pair, in-frame deletion called p.Met992del in the NF1 gene has a mild phenotype for people with the genetic disorder neurofibromatosis type 1, or NF1, the ...

In phase 2 trials, treatment with the combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor velpatasvir resulted in high rates of sustained virologic response in ...

The level of anticoagulation in response to a fixed-dose regimen of warfarin is difficult to predict during the initiation of therapy. We prospectively compared the effect of genotype-guided dosing ...

Lurbinectedin (PM01183), an active compound in platinum-resistant/refractory ovarian cancer (PRROC) patients: Results of a two-stage, controlled phase II study ...

All NDV field strains belong to a single serotype (APMV-1), so therefore standard vaccines (e.g. LaSota, B1) still can neutralize Genotype VII NDV: a change in genotype does not mean a change in ...