FDA committee unanimously recommends 1st mRNA flu vaccine
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Sustained and functional antibody responses to respiratory pathogens through vaccination is critical for global public health. The development and deployment of mRNA vaccines during the coronavirus disease 2019 (COVID-19) pandemic was a landmark ...
What is the full form of RNA? Explore its meaning, single-stranded structure, functions, how it differs from DNA, its role in protein synthesis, and its vital types like mRNA.
Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout cells using LNP. Cells with high or low GFP ...
A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study, recently ...
Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to create and grow tissue. And in the event of an immune response, different cells are shuttled around. While this process, known as ...
It took a global pandemic, but the critical role of messenger RNA in all of life's functions has taken center stage in the past year with the successful rollout of mRNA vaccines to combat the SARS-Cov-2 virus. In two new papers published the week of Jan ...
The tumor suppressor protein p53 plays a critical role in preventing cancer by regulating cell cycle, apoptosis, and genomic stability. However, mutations in the P53 gene are found in over 50% of human cancers, leading to loss of its protective function or ...
Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that this is possible with an innovative approach. In a study ...
Engineered extracellular vesicles delivering full-length DMD mRNA restored dystrophin and improved muscle strength and function in DMD models.
