A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...

Our brains integrate sensory, cognitive and internal state information with memories to extract behavioral relevance. Cortico–hippocampal interactions likely mediate this interplay, but underlying ...

Visual information is important for accurate spatial coding and memory-guided navigation. As a crucial area for spatial cognition, the medial entorhinal cortex (MEC) harbors diverse spatially tuned ...

This study illustrates the spatiotemporal dynamics of neuron subtype changes within the entorhinal cortex–hippocampal circuit during Alzheimer’s disease progression. EC-stellate neurons progressively ...

A longstanding question in neuroscience is how mammalian brains (including ours) adapt to external environments, information, and experiences. In a paradigm-shifting study published in Nature, ...

The human brain continues to be built after we are born for far longer than previously recognized, suggests research by Shawn Sorrells, assistant professor of neuroscience in the Kenneth P. Dietrich ...

Just as gravity explains how two distant objects can sway each other’s movement in space, synaptic connections may explain how amyloid plaques coax distant tau tangles to spread in the brain. This is ...

The representation of stimulus identity and experience is transformed from primary olfactory cortex to memory-related multisensory areas in the hippocampus.

Researchers have discovered the mechanistic steps underlying a new type of synaptic plasticity called behavioral timescale synaptic plasticity (BTSP). The study reveals how the entorhinal cortex (EC) ...