Chemotherapy drugs like doxorubicin and etoposide work by snapping a cancer cell’s DNA in two. The breaks are supposed to be ...

For decades, oncologists have watched a frustrating pattern repeat itself. Tumors fueled by the MYC protein, one of the most ...

A protein best known for driving cancer growth also helps damaged tumor cells survive by repairing their DNA, according to a ...

Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

Structural biologists at the University of Wisconsin-Madison today published cryo-electron microscopy structures of the complete bacterial DNA replication restart complex — a molecular machine that le ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...

Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...

Within the nucleus of every cell are long strings of DNA, the code that holds all the information needed to make and control every cell within a living organism. DNA, which stands for deoxyribonucleic ...