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College football odds, picks, predictions for Week 12, 2025: Computer backs Oklahoma and Miami
SEC heavyweight matchups highlight the slate of games to make Week 12 college football picks on with No. 4 Alabama (-6.5) vs. No. 11 Oklahoma and No. 10 Texas vs. No. 5 Georgia (-6.5) both set for Saturday as four of the nine winningest FBS programs all-time meet up.
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No. 7 Ole Miss (9-1, 5-1 SEC) will return to action on Saturday night for a primetime matchup against the Florida Gators at Vaught-Hemingway Stadium. In a match
The model is also backing Iowa (+6.5) to cover the spread on the road against USC, while the Over (52.5) hits 58% of the time in TCU vs. BYU. Before locking in your Week 12 college football picks, be sure to check out the top college football betting picks from SportsLine's advanced computer model.
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This article was originally published on www.si.com/college/lsu as Expert Computer Model Logs Final Pick Ahead of LSU Football vs. Arkansas Razorbacks. In a matchup that always delivers, the LSU Tigers will take the field in Death Valley for an SEC matchup against the Arkansas Razorbacks in Week 12.
The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.
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