Vemurafenib (V) in BRAF V600E metastatic melanoma (mM): Analysis of 507 patients (pts) enrolled in the French temporary authorization for use (ATU). This is an ASCO Meeting Abstract from the 2012 ASCO ...
The Cytogenetics Laboratory performs chromosome analysis, fluorescence in situ hybridization (FISH), and array comparative genomic hybridization (array CGH) on cells prepared from a wide variety of ...
Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
High-risk patients with genomically simple tumors, defined as ≤ 5 genomic changes, had improved recurrence-free and disease-specific survival compared with patients with complex tumors. Long-term ...
Santhosh Girirajan is the T. Ming Chu Professor of Biochemistry and Molecular Biology and Professor of Genomics at Penn State. The Girirajan Laboratory is interested in untangling the genetic and ...
Using SNP-CGH to Profile for Amplifications, Duplications, and Deletions The beginnings of personalized medicine have been forged by recent advances in SNP genotyping technologies. It is now possible ...
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