A growing body of researchers is utilizing optical imaging to monitor activity in the brain. One type of optical imaging, two-photon calcium imaging, has been widely adopted for its ability to record ...

Two-photon calcium imaging provides large-scale recordings of neuronal activities at cellular resolution. A robust, automated and high-speed pipeline to simultaneously segment the spatial footprints ...

The medial prefrontal cortex (mPFC) coordinates cognitive processes across multiple timescales, yet its role in multiple natural behaviors remain unclear. Existing neural recording methods are limited ...

Combining microscopy, scanning, and deep learning enables more precise imaging of functional dynamics in neural networks of human cortical organoids.

New ultra-fast sensors developed at Janelia can detect calcium ions nearly as fast as they are released from neurons, allowing scientists to tease out the individual, milliseconds-long signals passing ...