A missing piece in the cell death and inflammation signaling pathway puzzle has been revealed

An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways ...
BIOENGINEER

Fatty Liver Cells Turn On a Caspase-2 Death Pathway That Damps Hepatitis B Replication

New in vitro research shows that free fatty acid–induced steatosis activates a TNF-α/TNFR1–Caspase−8/Caspase−2 apoptotic ...
BIOENGINEER

Molecular Tags of Cell Death: How E3 Ubiquitin Ligases Steer Necroptosis in Cancer

A new review explains how E3 ubiquitin ligases attach molecular tags to the necroptosis machinery, shaping both cancer ...
Technology Networks

Missing Piece in the Cell Death Puzzle Revealed

Researchers identified HERC4 as a key regulator that activates TNF-induced apoptosis and necroptosis, revealing a potential ...
Informationsdienst Wissenschaft

One of the final pieces in the cell death and inflammation signalling pathway puzzle has been revealed

An international research team has discovered that the protein HERC4 is a key component in the signalling pathways involved in programmed cell death, which is responsible for triggering inflammatory ...
News Medical

Kinetic quantification of apoptosis using Incucyte® live-cell imaging assays

Apoptosis, or programmed cell death, is a tightly regulated biological process necessary for normal tissue maintenance and development. However, aberrations in apoptotic signaling networks are ...