Matthew Stafford passes for 280 yards and four touchdowns as the Rams defeat the 49ers 42-26 to set up an NFC West showdown with the Seattle Seahawks next week.

There is no shortage of bad blood between the Los Angeles Rams and San Francisco 49ers. The 49ers stunned the Rams just five weeks ago with an overtime win at SoFi Stadium. LA got back at San Francisco this week with a crushing loss that should force their division rival to look in the mirror and reconcile with the shortcomings of their roster.

All the energy in the world couldn’t overcome the 49ers losing two turnovers on a fumble by Jauan Jennings and an interception on fourth down by Jones. And also committing seven penalties for 45 yards to none for the Rams.

The Los Angeles Rams took care of the San Francisco 49ers via proper preparation and pure will on Sunday. 1. This was 'Peak McVay' Peak McVay refers to the phe

Even though the odds of the San Francisco 49ers completing the comeback still would have been slim, Fox’s officiating analyst said the referee crew’s mistake late in Sunday's loss to the Rams took away a key first down.

San Francisco 49ers starting quarterback Brock Purdy won't be active again Sunday vs. the Los Angeles Rams according to a report.

Matthew Stafford completes passes to eight receivers and throws touchdowns to four different players, becoming the fourth Ram and seventh quarterback in NFL history to throw four touchdowns in

It’s definitely a tough conference in my first year playing in it, and at this point we got to try and win every game we play in. Our backs are going to be

Defensive end Clelin Ferrell had a sack to help the 49ers beat the Giants last Sunday and he'll get another chance to rush the quarterback this Sunday.