In sweeping attacks that started early Friday, Israel has struck at the regime in Tehran, targeting Iranian nuclear and military assets. The Israeli strikes have killed more than 70 people, including four top security chiefs, and damaged Iran’s main nuclear site at Natanz.

Israel unleashed airstrikes across Iran for a third day on Sunday and threatened even greater force as some Iranian missiles evaded Israeli air defenses to strike buildings in the heart of the country.

After decades of enmity and conflict by proxy, it is the first time the arch-enemies have traded fire with such intensity, triggering fears of a prolonged conflict that could engulf the Middle East.

Experts suggest the U.S. has a strategic opportunity to leverage Iran's weakened position for a nuclear deal after Israel's targeted strikes on Iranian nuclear and military sites.

Iran launched dozens of ballistic missiles toward Israel on Friday night in retaliation for Israel's surprise attack early Friday. Israel struck at the heart of the Iran's nuclear program, killing several nuclear scientists as well as high-ranking military leaders, according to Israeli officials.

Mollie Hemingway, the editor in chief of The Federalist, warned that an escalation with Iran would cost Trump “really polling support that would be permanent,” and it would be seen as a “powerful gift” to the president’s “political enemies who still seek to destroy him and the movement he leads.”

Fox News’ Alex Hogan and Mark Meredith report on the strikes between Israel and Iran, and reaction from the United States. Heritage Foundation senior fellow Brent Sadler joins ‘Fox News Live’ to analyze the future of Iran’s nuclear program.

Iran launched dozens of ballistic missiles toward Israel on Friday night in retaliation for Israel's surprise attack early Friday. Israel struck at the heart of the Iran's nuclear program, killing several nuclear scientists as well as high-ranking military leaders, according to Israeli officials.

Israel warns "Tehran will burn" if Iran continues firing missiles, while state media say 60 people have been killed in a strike on Iran's capital.