Jaguars “experts” analyze Sunday’s 2025 Week 17 matchup between the Jaguars and Indianapolis Colts at Lucas Oil Stadium in Indianapolis, Ind.

The Colts are in danger of missing the postseason after a strong start to the 2025 regular season. Here are their playoff scenarios after Week 16.

There are 13 Indianapolis Colts players listed on the team's first Week 17 injury report ahead of Sunday's game with the Jacksonville Jaguars. Of note, Wednesday's practice was a walkthrough so the official injury report is an estimation.

Indianapolis Colts lose to the San Francisco 49ers and now are lost moving forward in the AFC South and AFC Conference.

The Indianapolis Colts are going with 44-year-old quarterback Philip Rivers again. The San Francisco 49ers are battling for NFC playoff position.

Brock Purdy and the San Francisco 49ers spoiled Philip Rivers' return to Indianapolis, as they took down the Colts to remain in contention for the top seed in the NFC.

The 49ers are coming off a win over the Titans following their bye week, their fourth consecutive win after a loss to the Rams had dropped them to 6-4 on the year. The playoff-bound Niners got another massive favor from the Seahawks on Thursday night, and they now control their own destiny in the race for the No. 1 seed in the NFC.

The Jacksonville Jaguars have preached next man up all season, and they might need to turn to that mantra again versus the Indianapolis Colts in Week 17.