As the 49ers prepare for Sunday’s matchup against the Tennessee Titans, McCaffrey’s availability has become a storyline. Earlier in the week, he battled an illness that limited his practice time, though he was able to log a full session on Friday.

Riding a three-game winning streak into the Bye Week had to have put the San Francisco 49ers on cloud nine. But what probably put them there the most was their

Los 49ers de San Francisco colocaron al receptor Brandon Aiyuk en la lista de reserva, lo que lo hace inelegible para regresar de una lesión de rodilla esta temporada.

Our experts' predictions are in for Tennessee Titans vs. San Francisco 49ers on Sunday. Here's who our experts are picking to win the Week 15 NFL game.

However, Purdy was incredible in that game. His stats weren’t anything special, but he played a clean, smart, and impactful game. What allowed Purdy to play so well was thanks to the critical aspect that the 49ers coaches were emphasizing during the week.

The Tennessee Titans and the San Francisco 49ers meet Sunday in Week 15 in Santa Clara, California, with kickoff slated for 4:25 p.m. ET.

The Tennessee Titans and San Francisco 49ers face off in Week 15 action this Sunday at Levi's Stadium. Literally no one expects the Titans to win this game, and it's unlikely the Titans can keep the score close. The 49ers are in the playoff hunt and will be fresh off their bye week, while the Titans are on a different trajectory.

The San Francisco 49ers are sitting at 9-4 with four weeks left in what has been quite the season this year. They’ve dealt with injuries, another wide receiver saga, and still have managed to be in the playoff picture despite playing a number of first and second-year players this season.